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Updated: Sep 16, 2025

Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
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用单分子成像阐明内在失序蛋白在真核生物转录调节中的作用

Shawn Yoshida1, Yanghao Zhong2, Jonathan Banh2

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Journal of molecular biology
|July 11, 2025
PubMed
概括

内在无序蛋白质 (IDP) 缺乏稳定的结构,但对于转录等细胞功能至关重要. 单分子成像揭示了它们的动态行为,为基因调节提供了新的见解.

关键词:
转录法规 转录法规本质上是无序的蛋白质.单分子光显微镜

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