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关于TIM-3连接体对NK细胞功能差异影响的评论

Rieneke van de Ven1,2

  • 1Otolaryngology/Head and Neck Surgery, Amsterdam UMC-Locatie VUMC, Amsterdam, The Netherlands r.vandeven@amsterdamumc.nl.

Journal for immunotherapy of cancer
|July 11, 2025
PubMed
概括

向T细胞免疫球蛋白和含有分子3 (TIM-3) 的粘素域限制了癌症免疫疗法的成功. 研究人员发现,加勒-9通过TIM-3抑制自然杀手 (NK) 细胞功能,影响头癌患者的存活率.

关键词:
头部和部癌症 头部和部癌症免疫检查点抑制剂 免疫检查点抑制剂免疫调节器 免疫调节器自然杀手 - - NK - - 是一种自然杀手.

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