血管内化疗治疗出血的头部和部瘤:一个单一中心的经验
Raghav Mattay1,2, Woody Han2,3, Sartaaj Walia2
1Neurosurgery, Northwell Health, New Hyde Park, New York, USA.
Journal of neurointerventional surgery
|July 11, 2025
概括
带有栓塞的动脉内 (IA) 化疗有效控制了晚期头癌的出血,实现了显著的瘤减少和防止再次出血. 这种结合的方法显示出对管理这些具有挑战性的恶性瘤的希望.
科学领域:
- 在瘤学瘤学.
- 干预性放射学 干预性放射学
- 头部和部手术 头部和部手术
背景情况:
- 晚期头癌具有显著的发病率和死亡率.
- 与瘤相关的出血需要复杂的治疗干预.
- 内动脉 (IA) 化疗与栓塞结合,是治疗出血性恶性瘤的潜在策略.
研究的目的:
- 评估IA化疗与栓塞的安全性和有效性.
- 为了评估患有头部和部恶性瘤出血的患者的结果.
主要方法:
- 五名患有晚期头癌的患者的回顾性病例系列.
- 通过选择性导管注射使用西斯或碳乙烯的IA化学栓塞.
- 通过3D体积分析评估瘤反应;评估出血控制,进展和并发症的结果.
主要成果:
- 所有患者都实现了局部瘤控制,平均体积减少66% (范围为29-84%).
- 在8个月的平均随访期间没有观察到再出血.
- 治疗部位的客观反应;两名患者经历了急性损伤,一名患有膜缩.
结论:
- 带有栓塞的IA化疗是一种安全有效的方法,用于治疗出血发达的头癌.
- 该组合可提供局部瘤控制,并降低再出血的风险.
- 需要进行更大规模的研究来确认其临床实用性.
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