在单一中心的活体脏捐赠者中功能中期结果
İbrahim Furkan Küçük1, Necattin Fırat1, Fatih Altıntoprak1
1Department of General Surgery, Medicine Faculty, Sakarya University, Sakarya, Turkey.
Transplantation proceedings
|July 11, 2025
概括
活体捐赠者切除术 (LDN) 是安全的,但捐赠者可能会经历暂时的功能变化. 长期风险是最小的,一些因素,如男性性别和50岁以上的年龄可能会影响恢复.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 活体捐赠者切除术 (LDN) 是移植的一个常见程序.
- 虽然通常被认为是安全的,但了解捐赠者的长期功能变化至关重要.
研究的目的:
- 评估LDN之前和之后的功能变化.
- 在活着的脏捐赠者中确定与持续性功能障碍相关的风险因素.
主要方法:
- 对110名接受了LDN的活体脏捐赠者的回顾性分析.
- 术前和1年术后的功能测试,脏大小和血液/尿液参数的比较.
主要成果:
- 脏大小显著增加,而估计的球过率 (e-GFR) 在LDN后1年显著下降.
- 尿中蛋白质肌素比率 (PCR),血清肌素,TSH和水平显著增加.
- 在男性和50岁以上的个体中观察到较高的血清肌素增加率.
结论:
- 活着的脏捐赠者可能经历过渡性功能障碍脏切除术后.
- 尽管存在潜在的变化,但对精心挑选的捐赠者来说,长期结果通常是安全的,风险是可以承受的.
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