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气温上升有助于西尼罗河病毒的多样化和传播潜力的增加
Rachel L Fay1,2,3, Mauricio Cruz-Loya4, Joseph G Maffei5
1Department of Biomedical Sciences, University at Albany College of Integrated Health Sciences, Rensselaer, NY, USA. rachellfay@gmail.com.
Scientific reports
|July 11, 2025
概括
气候变暖正在推动西尼罗河病毒 (WNV) 的进化. 当代WNV菌株在更高的温度下显示出更高的传播潜力,这表明它们适应了更温暖的气候.
科学领域:
- 环境科学 环境科学
- 病毒学 病毒学
- 流行病学 流行病学
背景情况:
- 西尼罗河病毒 (WNV) 是美国大陆最常见的蚊子传播疾病,自1999年以来在纽约州 (NYS) 流行.
- 纽约州气温的上升与WNV传播的增加相关,这对公众健康造成了担忧.
研究的目的:
- 调查温度上升是否会影响WNV的多样化和适应.
- 为了确定当代WNV菌株与历史菌株相比,在高温下是否具有更高的传播潜力.
主要方法:
- 来自纽约州蚊子的WNV监测和测序数据的分析.
- 来自温暖的 (2017-2018) 和凉爽的 (2003-2004) 夏季的WNV菌株的比较.
- 评估Culex pipiens的传播效率,并计算不同温度下的相对R0.
主要成果:
- 在温度上升,WNV遗传多样性增加和更高的流行率之间发现了显著的相关性.
- 当代WNV菌株在温度升高 (20°C,24°C,28°C) 时表现出更高的传播潜力.
- 当代WNV菌株表现出更大的表型和基因型多样性.
结论:
- 气候变暖和病毒适应可能推动了具有增强传播潜力的WNV菌株的出现.
- 温氏河流病毒适应较高的温度可能会导致流行地区的传播风险增加.
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