在巴西一个中等的人类发展指数的州,子宫癌净生存率的趋势
Brenda Evelin Barreto da Silva1,2, Veronica Di Carlo3, Pamela Minicozzi3
1Health Sciences Graduate Programme, Federal University of Sergipe, Aracaju, Sergipe, Brazil. brendaevelinbarreto@gmail.com.
Scientific reports
|July 11, 2025
概括
在巴西东北部,子宫癌的存活率在过去二十年中大幅下降. 这一趋势凸显了改善癌症查和妇女及时获得治疗的迫切需要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 宫癌是巴西东北部的一个重大公共卫生问题,是女性第二常见的癌症.
- 之前的研究缺乏长期的,基于人口的存活数据,用于该地区的宫癌.
研究的目的:
- 提供第一个长期,基于人口的宫癌净存活率估计在巴西塞尔吉佩.
- 分析子宫癌存活率的趋势随着时间的推移和根据组织学亚型.
主要方法:
- 分析了3,977例在1996年至2017年期间在塞尔吉佩诊断的侵袭性宫癌病例.
- 排除了6095个in situ新生体.
- 使用Pohar Perme方法估计的净生存率,按组织学和日历时期分层,并根据年龄标准化.
主要成果:
- 观察到宫癌的净存活率大幅下降.
- 一年净生存率从84.6% (1996-1999) 降至73.4% (2015-2017年). 这是一个非常好的例子.
- 在研究期间,五年净生存率从60.8%下降到49.3%;状细胞癌和腺癌显示出相似的生存率 (55-58%).
结论:
- 生存率下降的趋势表明,晚期或侵袭性宫癌的潜在增加.
- 导致生存率下降的因素包括延迟诊断和低于最佳治疗.
- 有必要加强宫癌查计划,确保及时获得癌症治疗.
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