相关实验视频
Updated: Sep 16, 2025
03:36
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
533
血清性酸酶升高作为消化系统癌症的手术前皮性生物标志物:一个回顾性队列研究
Kohta Asano1,2, Kae Tachibana3, Satoru Shinoda4
1Department of Rehabilitation Medicine, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan. uncle_harry.7@outlook.com.
概括
血清性酸酶 (ALP) 升高可能表明在术前消化道癌症患者中存在症风险. 这种慢性炎症标志物可以帮助确定在手术前需要干预的患者.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 老年病的医生 老年病的医生
- 生物化学 生物化学
背景情况:
- 肉症与手术前患者的预后不佳和术后并发症有关.
- 癌症患者的肉类的机制尚未完全理解.
- 慢性炎症与sarcopenia的发展有关.
研究的目的:
- 调查血清性酸酶 (ALP) 的升高是否可以作为消化系统癌症患者手术前的肉症标志物.
- 在这个患者群体中,探索ALP指示的慢性炎症和肉症之间的关联.
主要方法:
- 对274名消化道癌症患者的电子病历进行了回顾性分析.
- 根据外科手术前查,患者被分类为sarcopenia (SC) 和non-sarcopenia (NSC) 组.
- 进行了统计分析,考虑了诸如年龄,肝功能和骨折等混因素.
主要成果:
- 血清ALP水平在肉症组 (168.4U/L) 与非肉症组 (100.4U/L) 相比显著更高.
- 升高的ALP与肉症风险有显著的相关性 (p=0.0018,OR=1.0055).
- 观察到组之间的白蛋白,血红蛋白,中性粒细胞与淋巴细胞的比率以及营养不良参数之间存在显著差异.
结论:
- 血清ALP升高,可能是由于慢性炎症,与手术前消化系统癌症患者的肉类相关.
- 在这种人群中,ALP可以作为一种有用的生物标志物来识别肉症风险.
相关概念视频
01:30Serum Laboratory Studies, Stool Test, Breath Test
476
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
476
01:24Serum Studies: Renal Function Tests
48
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
48