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Updated: Sep 16, 2025

Protocol for MicroRNA Transfer into Adult Bone Marrow-derived Hematopoietic Stem Cells to Enable Cell Engineering Combined with Magnetic Targeting
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Published on: June 18, 2018

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通过骨髓向的工程外体来抑制USP5,用于骨髓扩散性瘤治疗

Wenjun Wang1,2,3, Yufeng Jiang4, Donglei Zhang1

  • 1Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.

Journal of nanobiotechnology
|July 11, 2025
PubMed
概括

研究人员确定USP5是骨髓增殖性新生瘤 (MPNs) 的关键驱动因素. 他们开发了向外体,以提供USP5抑制剂,显著减少癌细胞生长,并改善MPN模型中的存活率.

关键词:
骨髓准的目标是骨髓脱基化酶是一种脱基化酶.介质细胞干细胞 介质细胞干细胞骨髓增殖性瘤是一种多发性瘤.

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