饮食习惯是哈西莫托甲状腺炎和骨质疏松症之间缺失的联系吗?
Anita Vergatti1, Veronica Abate1, Francesca Garofano1
1Department of Clincal Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.
Nutrients
|July 12, 2025
概括
哈西莫托的甲状腺炎通过炎症和改变的甲状腺激素导致骨质疏松症. 饮食因素,如地中海饮食,可能有助于减轻这种情况的骨损失.
科学领域:
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
- 骨生物学 骨生物学 骨生物学
背景情况:
- 骨代谢涉及到平衡的骨质母细胞和骨质母细胞活动.
- 骨质疏松症是一种全球代谢性骨疾病.
- 哈西莫托的甲状腺炎 (HT),一种自身免疫性甲状腺疾病,越来越多地与骨质损失有关.
研究的目的:
- 审查将哈西莫托甲状腺炎与骨代谢障碍联系在一起的证据.
- 探索自身免疫性甲状腺疾病中骨脆弱性的多因素性质.
- 突出饮食在减轻与HT相关的骨损失方面的潜在作用.
主要方法:
- 整合当前的临床和实验证据.
- 专注于甲状腺功能,免疫失调和骨重塑之间的相互作用.
- 考虑营养因素,如,和饮食模式.
主要成果:
- 即使在无甲状腺状态下,HT也可以通过炎症和自身抗体改变骨重塑.
- 亚临床甲状腺功能低下或甲状腺功能过高 (低TSH,高THs) 与骨矿物质密度 (BMD) 降低和骨折风险增加有关.
- 营养因素,包括,和富含抗氧化剂的饮食 (例如地中海饮食),可能会影响甲状腺和骨的健康.
结论:
- 哈西莫托的甲状腺炎是骨脆弱的一个重要因素.
- 在HT中,骨损失是多因素的,涉及荷尔蒙,炎症和潜在的营养方面.
- 饮食干预措施可能在HT患者的骨健康管理中发挥作用.
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