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在患有疾病相关营养不良的患者中,口服摄入量和萨科佩尼亚之间的关系
Paloma Pérez-López1,2, Juan José López-Gómez1,2, Olatz Izaola-Jauregui2
1Hospital Clínico Universitario de Valladolid, 47003 Valladolid, Spain.
对患有疾病相关营养不良 (DRM) 的患者来说,营养摄入量至关重要. 摄入不足的卡路里和蛋白质会增加患上肉症的风险,这种疾病的特征是肌肉损失.
科学领域:
- 老年学是一门学科.
- 临床营养学 临床营养学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 在患有疾病相关营养不良 (DRM) 和肉类症的患者中评估口服摄入量是临床上具有挑战性的.
- 标志着肌肉质量损失的萨尔科佩尼亚,经常与营养不良并存,使患者管理复杂化.
- 了解营养摄入量和肉症之间的相互作用对于有效的治疗策略至关重要.
研究的目的:
- 为了研究口服摄入与营养需求相对的关系,以及DRM患者中肉类的存在.
- 量化与不充分的热量和蛋白质消费相关的缩症和严重营养不良风险.
主要方法:
- 一项针对118名DRM门诊患者的前性观察性研究,使用全球营养不良领导倡议的标准进行诊断.
- Sarcopenia评估遵循了欧洲老年人肉症工作组的标准.
- 分析了为期3天的饮食记录,以计算能量和蛋白质摄入量,与估计需求进行比较 (哈里斯-本尼迪克特方程,1.5g/kg/day蛋白质).
主要成果:
- 在42%的患者中发现了sarcopenia;在sarcopenic和非sarcopenic组之间没有观察到显著的BMI差异.
- 患有皮症的患者显著降低了热量和宏观营养素摄入量.
- 不足够的能量 (<70%的需求) 和蛋白质摄入 (<70%的需求) 与较高的肉类的患病率有关.
- 低蛋白质摄入量显著增加了萨尔科佩尼亚 (OR:4.27) 和严重营养不良 (OR:5.17) 的风险.
结论:
- 摄入不够的热量和蛋白质与DRM患者中高患肉症的患病率有关.
- 在这种患者群体中,减少蛋白质摄入量是沙科佩尼亚和严重营养不良的重要危险因素.
- 优化营养摄入量,特别是蛋白质,对于治疗DRM患者的肉症至关重要.
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