现代营养科学中的功能性食品:机制,证据和公共卫生影响
Mónika Fekete1,2,3, Andrea Lehoczki1,2,3, Agata Kryczyk-Poprawa4
1Institute of Preventive Medicine and Public Health, Faculty of Medicine, Semmelweis University, 1085 Budapest, Hungary.
Nutrients
|July 12, 2025
概括
功能性食品提供健康益处超出了基本营养,有助于预防慢性疾病. 它们融入饮食是有希望的,但在可访问性和采用性方面面临挑战.
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
- 生物化学 生物化学
背景情况:
- 功能性食品对基本营养之外的健康益处越来越感兴趣.
- 国际机构将其定义为含有用于预防疾病的生物活性成分.
- 这反映了向积极主动,以健康为导向的饮食策略 ("食物作为药物") 的转变.
研究的目的:
- 提供功能性食品的全面,跨学科的概述.
- 检查它们的生物机制,临床证据和公共卫生意义.
- 探索个性化营养和营养基因组学的未来前景.
主要方法:
- 对最近的同行评审研究和卫生当局指导方针进行了彻底的文献审查.
- 检查特定的生物活性化合物及其作用.
- 临床证据,监管框架和采用挑战的分析.
主要成果:
- 特定的化合物 (益生菌,多,欧米茄-3,维生素/矿物质) 显示了诸如改善肠道健康,减少炎症,心脏代谢调节和免疫支持等益处.
- 临床试验支持降低LDL胆固醇,提高胰岛素敏感性和减轻氧化应激等益处.
- 广泛采用的挑战包括社会经济差异和有限的健康素养.
结论:
- 功能性食品是以预防为重点的医疗保健的一个有希望的组成部分.
- 为了最大限度地发挥它们的影响,需要一个协调的,基于证据的方法,涉及多个利益相关者.
- 人工智能,微生物组研究和基因组学方面的未来创新可能会增强它们的目标应用.
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