对多发性骨髓瘤相关骨疾病的支持性护理的进展-一篇评论
Saadia Abbas1, Haleema Sadia Adil2, Shahzad Raza3
1Medical College, Aga Khan University, Karachi 74800, Pakistan.
Cancers
|July 12, 2025
概括
多发性骨髓瘤患者经常患有骨病,这是一个严重的并发症. 本综述涵盖了当前的双酸盐使用以及用于管理骨髓瘤骨病及其并发症的新疗法.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 骨生物学 骨生物学 骨生物学
背景情况:
- 多发性骨髓瘤 (MM) 是一种引起骨损伤的血细胞癌症.
- 在MM中,骨解性骨病导致疼痛和骨折,增加死亡率.
- 骨并发症的有效管理对于MM患者的生活质量至关重要.
研究的目的:
- 审查骨髓瘤骨病 (MBD) 管理方面的进展.
- 总结MBD和相关不良事件的基于证据的策略.
- 突出双酸盐指南和正在开发的新疗法.
主要方法:
- 对最近的科学文献进行叙述性回顾.
- 对MBD当前治疗指南的分析.
- 对MM骨并发症的新兴治疗药物的概述.
主要成果:
- 双酸盐是减少MBD骨事件的标准.
- 新的疗法显示出改善MM患者治疗结果的希望.
- 了解MM的病理生理学推动了新疗法的开发.
结论:
- 最佳的MBD管理需要与抗MM疗法一起进行综合护理.
- 目前的指导方针强调适当使用双酸盐.
- 新兴的治疗方法为患有骨髓瘤骨病的患者提供了新的希望.
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