患有扩散型大B细胞淋巴瘤的患者的癌症和化疗诱导的大脑新陈代谢变化:一系列FDG PET研究
Insung Chung1, Yeon-Koo Kang1, Jae Won Min1
1Division of Nuclear Medicine, Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Cancers
|July 12, 2025
概括
癌症治疗可能会导致认知障碍,通常被称为"化疗大脑". 本研究探讨了这些变化在治疗期间对患者的影响.
科学领域:
- 在瘤学瘤学.
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
背景情况:
- 认知障碍是癌症及其治疗的已知副作用之一.
- 具体的机制和患者经验需要进一步研究.
研究的目的:
- 研究正在接受治疗的癌症患者认知障碍的患病率和特征.
- 了解患者对认知变化的主观经验.
主要方法:
- 使用标准化神经心理测试对认知功能进行纵向评估.
- 患者报告的主观认知投诉的结果措施.
- 探索潜在的促成因素,如治疗类型和心理痛苦.
主要成果:
- 在一小部分患者中观察到注意力,记忆力和执行功能的显著缺陷.
- 主观认知投诉与客观测试成绩相关联.
- 治疗强度和持续时间与更大的认知障碍有关.
结论:
- 认知障碍是癌症患者在治疗期间普遍和具有影响力的问题.
- 早期识别和支持性干预对于管理这些影响至关重要.
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