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Updated: Sep 16, 2025

Visualizing DNA Damage Repair Proteins in Patient-Derived Ovarian Cancer Organoids via Immunofluorescence Assays
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在卵巢小细胞癌中,MYC调节DNA修复基因表达程序,超血型卵巢癌

James R Evans1,2, Jing Wang3,4, Cinthia N Reed1,2

  • 1Department of Biology, Middle Tennessee State University, Murfreesboro, TN 37132, USA.

Cancers
|July 12, 2025
PubMed
概括

MYC驱动小细胞卵巢癌 (SCCOHT) 中的DNA修复基因表达,这是一种与SWI/SNF突变相关的癌症. 恢复BRG1可以抵消这种MYC程序,为SCCOHT提供治疗点.

关键词:
这是一个ATRATRATRATR.这就是BRG1的原因.修复DNA的修复DNA的修复我的世界 MYC斯科特 (SCCOHT) 是一个小岛屿.这就是SMARCA4的标志.在SNF5中,SNF5是SNF5.在 SWI/SNF 中.卵巢 卵巢 的 卵巢这种瘤是rhabdoid瘤.

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