增强骨生长和面形态学预测工具在综合性骨突症:重点是基变量
Lantian Zheng1, Norli Anida Abdullah2,3, Norlisah Mohd Ramli4
1Department of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Diagnostics (Basel, Switzerland)
|July 12, 2025
概括
使用稳定的头骨基数变量的预测模型可以估计患有综合征性头骨缩症 (SC) 的儿童的中脸部生长. 这些工具有助于了解面形态,并改善SC患者的术后结果.
科学领域:
- 面外科手术 面外科手术
- 儿童整形手术 儿童整形手术
- 医学成像分析分析 医学成像分析
背景情况:
- 综合性关节缩症 (SC) 呈现出复杂的面形,影响手术结果.
- 在SC的变化需要可靠的方法来预测中面生长.
- 了解面形态对于管理SC患者至关重要.
研究的目的:
- 开发和验证SC患者中部面部变化的预测模型.
- 为了利用稳定的基变量进行生长预测.
- 探索SC儿童的面形态.
主要方法:
- 在17名SC患者和对照组中,对骨底部和中脸部变量的分析.
- 应用曼·惠特尼U测试和皮尔森相关性.
- 多重线性回归与三倍交叉验证用于预测模型开发.
主要成果:
- 在SC患者中,基缩短,基角度改变.
- 显著减少中脸长度和腹肌长度,增加中脸宽度.
- 经过验证的回归模型以高准确度 (R2 > 0.87) 预测中面长度,宽度和双肩长度.
结论:
- 开发的预测模型显示了估计SC儿童中部面部生长的潜力.
- 稳定的底变量有效预测面部中部的变化.
- 这些模型可以帮助进行SC的术前规划和管理.
相关概念视频
Sutures of the Skull
7.7K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
7.7K
Cranial Bones: Lateral View
2.7K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
2.7K
Cranial Bones: Superior and Posterior View
2.9K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
2.9K
Overview of the Skull
5.4K
The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
5.4K
Growth of Cartilage and Bone Tissue
3.5K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.5K


