在Galdieriales中的膜传送器的马赛克进化
Claudia Ciniglia1, Antonino Pollio2, Elio Pozzuoli1
1Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "L. Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
Plants (Basel, Switzerland)
|July 12, 2025
概括
红藻膜运输体显示出混合的进化历史. 一些家庭通过横向基因转移获得基因,而另一些家庭则通过垂直遗传,帮助极端动物适应.
科学领域:
- * 基因组学和分子生物学
- * 藻类生物学 藻类生物学
- * 进化生物学 进化生物学
背景情况:
- * 膜载体对于细胞溶液运输至关重要,特别是在像Galdieriales红藻这样的极端动物中.
- * 这些藻类居住在极端环境 (地热,金属丰富) 中,并拥有适应性的传送系统,以实现代谢灵活性.
- *之前的研究已经在*Galdieria sulphuraria*中发现了传送基因,但它们的进化起源需要进一步调查.
研究的目的:
- * 在Galdieriales中对三个关键的传送者家族 (MFS,APC,Nramp) 进行比较的基因分析.
- * 调查这些转载体的进化起源和潜在的水平基因转移 (HGT) 事件.
- * 了解极性红藻对环境弹性的基因组基础.
主要方法:
- * 转载基因家族 (MFS,APC,Nramp) 的基因分析比较.
- *从*Galdieria sulphuraria*菌株SAG 107.79.9中选择过度表达的转录
- *使用Galdieriales和多种正统序列重建最大概率树.
主要成果:
- *主要促进者超级家族 (MFS) 糖载体 (SPs) 显示多性和真菌亲和,表明多个HGT事件.
- *在MFS中,酸盐:H+同胞体 (PHS) 形成了一个单类群,表明垂直遗传.
- * 氨基酸-聚胺-有机化 (APC) 载体似乎源于 prokaryotic,仅在 * G. sulphuraria * 和极端的 prokaryotes 中发现.
- *自然耐药性相关的巨细胞蛋白 (Nramp) 载体在 prokaryotes 和 eukaryotes 中大致保留,没有最近 HGT 的证据.
结论:
- * Galdieriales 膜载体表现出一幅马赛克式的进化历史,由垂直遗传和水平基因获取形成.
- * 有证据表明多个HGT事件,特别是MFS糖载体,有助于这些红藻的适应.
- *这项研究提供了对基因组策略的见解,使极端友红藻能够在恶劣环境中壮成长.
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