在长期使用机械通风的患者中,断奶成功的预测因素:回顾性队列研究
Bartal Amir1, Ofri Mai1,2, Turgeman Shira1
1Internal Medicine Department, Soroka University Medical Center, Ben Gurion University of Negev, Beer Sheva P.O. Box 151, Israel.
在长时间的机械通风中预测断奶成功至关重要. 低白蛋白和高SOFA在入院时的得分识别患者可能会失败,指导未来的干预措施,以获得更好的结果.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 重症监护病房 (ICU) 管理管理
背景情况:
- 断奶失败对长期使用机械呼吸系统的患者来说是一个重大挑战.
- 确定成功断奶的预测因素对于改善患者的治疗结果和资源配置至关重要.
研究的目的:
- 描述14天以上需要机械通风的患者的结果.
- 在这个患者队列中确定机械通风成功断奶的特定预测因素.
主要方法:
- 索罗卡大学医学中心88名患者的回顾性分析.
- 成功断奶 (SW) 和失败断奶 (FW) 组之间的结果比较.
- 多变量后勤回归分析以确定断奶成功的预测因素.
主要成果:
- 45%的患者成功奶并出院.
- 住院死亡率为28%,仅限于失败的断奶组 (p < 0.001).
- 低albuminemia和更高的序列器官衰竭评估 (SOFA) 在入院时的得分预测了断奶失败 (OR:分别为5.71和0.54).
结论:
- 入院时的低白蛋白和SOFA分数是14天以上通风患者断奶成功的关键预测指标.
- 年龄和并发症并不是显著的预测因素.
- 建议对白蛋白补充剂和高蛋白饮食进行前性研究.
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