基于人工智能的预测模型的开发,用于从全景射线图中诊断绝经后妇女的骨质疏松症
Francesco Fanelli1, Giuseppe Guglielmi1, Giuseppe Troiano2
1Department of Clinical and Experimental medicine, University of Foggia, 71122 Foggia, Italy.
Journal of clinical medicine
|July 12, 2025
概括
人工智能模型可以使用全景放射图预测绝经后妇女的骨质疏松风险. 深度放射学和CNN显示为机会性查有前途,但需要进一步验证用于临床使用.
科学领域:
- 人工智能的人工智能
- 放射学 放射学是一门学科.
- 骨质疏松症研究 骨质疏松症研究
背景情况:
- 骨质疏松症对绝经后妇女构成重大健康风险.
- 目前用于骨质疏松症的诊断方法可能是侵入性的或昂贵的.
- 全景射线图 (OPT) 是广泛可用的牙科成像工具.
研究的目的:
- 开发和评估基于人工智能的骨质疏松风险评估预测模型.
- 为了利用全景放射图用于骨质疏松症的机会性查.
- 为了比较经典放射学,深度放射学和卷积神经网络 (CNN) 的性能.
主要方法:
- 从绝经后妇女收集了301个OPT,用DXA作为基本真相.
- 在245个OPT上训练并内部测试模型;在56个OPT上进行外部验证.
- 开发了使用经典放射学,深度放射学 (DenseNet-121) 和CNN (ResNet-50) 的模型.
主要成果:
- 经典放射学显示出有限的预测能力 (AUC = 0.514).
- 通过逻辑回归实现了深度放射学AUC = 0.722.2.
- ResNet-50 CNN获得了最高的外部验证AUC (0.786) 与90.5%的灵敏度.
结论:
- 人工智能模型显示了通过OPT进行机会性骨质疏松症查的潜力.
- 深度放射学和转移学习策略显示出有希望的结果.
- 进一步对不同种群进行验证对于临床实施至关重要.
关键词:
双能X射线吸收仪 (DXA) 是一种双能X射线吸收仪.卷积神经网络 (CNN) 是一种神经网络.深度放射学是指深度的放射学.骨质疏松症的诊断 骨质疏松症的诊断全景X射线图的使用.绝经后的妇女 绝经后的妇女无线电学 (radiomics) 是一种无线电学.转移学习转移学习更多相关视频
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