慢性疾病中的缺铁和缺铁性贫血 - - 常见,重要,可治疗
Bjørn Moum1,2, Stefan Lindgren3
1Institute of Clinical Medicine, University of Oslo, 0316 Oslo, Norway.
Journal of clinical medicine
|July 12, 2025
概括
铁对能量和血红蛋白至关重要. 缺铁导致贫血,原因是缺铁,摄入不良,吸收问题或炎症. 口服铁是首选的,但静脉注射铁用于严重病例或当口服治疗失败时.
科学领域:
- 生物化学 生物化学
- 血液学 血液学 血液学
- 营养 营养 营养 营养 营养
背景情况:
- 铁对于能量代谢和血红蛋白合成至关重要.
- 铁缺乏症可能是由于损失增加,摄入不足,肠道吸收不良或炎症期间释放受损而引起的.
- 贫血是由于铁库耗尽或铁利用能力受损而导致的.
研究的目的:
- 概述铁在人体中的作用.
- 描述铁缺乏的原因和后果.
- 介绍铁缺乏性贫血的治疗策略.
主要方法:
- 关于铁代谢和贫血的文献综述.
- 分析导致缺铁的因素.
- 口服和静脉注射铁治疗方式的比较.
主要成果:
- 血红蛋白合成优先于其他铁功能.
- 系统性炎症可能会影响储存中的铁的释放.
- 口服铁是没有炎症的健康个体的主要治疗方法.
结论:
- 缺铁导致贫血,当储量受到损害或利用受到阻碍时.
- 静脉注射铁适用于口服治疗失败,不耐受性或严重贫血时需要快速纠正.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
103
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
103
Disorders of Erythrocytes
1.3K
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
1.3K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.9K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.9K
Chronic Bowel Disorders: Introduction
541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541
Chronic Kidney Disease III: Interprofessional Care
81
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
81
Chronic Pancreatitis I: Introduction
166
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
166


