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Updated: Sep 16, 2025

A High-Throughput Enzyme-Coupled Activity Assay to Probe Small Molecule Interaction with the dNTPase SAMHD1
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Published on: April 16, 2021

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药物gemcitabine和核基中的分子内与分子间结合:一项计算研究

Natarajan Sathiyamoorthy Venkataramanan1, Ambigapathy Suvitha2, Ryoji Sahara3

  • 1Department of Chemistry, School of Engineering, Dayanada Sagar University, Bangalore 562 112, India.

Molecules (Basel, Switzerland)
|July 12, 2025
PubMed
概括

这项研究揭示了citabine (一种化疗药物) 与核基形成稳定的复合体,主要是通过键. 关氨酸形成了最强的键,表明了潜在的药物-DNA相互作用.

关键词:
DFT计算的计算方法毒品 毒品 毒品 是一种药物.能量分解分析分析.非共价相互作用非共价相互作用核基是核基的组成部分.

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