聚烯和聚乙烯四甲酸微塑料对青素结构和功能的影响
Tamara Lujic1, Nikola Gligorijevic2, Dragana Stanic-Vucinic1
1University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia.
International journal of molecular sciences
|July 12, 2025
概括
微塑料 (MP) 与素和食物蛋白质等消化酶相互作用,形成蛋白质冠状. 然而,现实的MP度不太可能显著影响肉蛋白或过敏原消化.
科学领域:
- 环境科学 环境科学
- 生物化学 生物化学
- 食品科学 食品科学 食品科学
背景情况:
- 摄入微塑料 (MP) 是人类和动物的重要暴露途径.
- 在消化过程中,MP与胃肠道酶和食物蛋白相互作用.
研究的目的:
- 研究素在聚烯 (PP) 和聚乙烯四甲酸盐 (PET) MP 上的吸附.
- 评估MP对素结构和活性的影响.
- 在MP的存在下,在实验室中评估牛肉提取物 (BME) 蛋白质和过敏原的素消化能力.
主要方法:
- 研究了MPs上的蛋白质冠状形成 (软硬).
- 分析了素吸附,结构变化和活动丧失.
- 使用体外试验测试评估蛋白质和过敏原的消化能力.
主要成果:
- 素,BME蛋白和过敏原形成了MP的动态冠状.
- 硬冠中的素失去了显著的活性;其他地方发生了轻微的结构变化.
- MPs稍微减缓了38kDa蛋白质的消化,但没有影响a-Gal携带的过敏原.
结论:
- 在肠道中现实的MP度不太可能显著影响肉蛋白或过敏原的易消化性.
- 在MPs上的蛋白质冠状体由BME质和过敏原蛋白质组成.
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