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对人类激活诱导的cytidine降氨酶SNP的洞察力 AID AID

Ekaterina A Koveshnikova1, Aleksandra A Kuznetsova1

  • 1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.

International journal of molecular sciences
|July 12, 2025
PubMed
概括

DNA-deaminase AID对于适应性免疫至关重要,但其失调会导致疾病. 艾滋病的遗传变异可能会对其功能产生负面影响,可能导致免疫障碍和癌症.

关键词:
氨基酸替代物对酶功能的影响人类激活诱导的cytidine除氨酶 AID.在SNP效应的形评估中.单核酸多态 SNP 单核酸多态

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