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Updated: Sep 16, 2025

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针对PAD4:对抗1型糖尿病中的β细胞损失的有希望的策略

Hsu Lin Kang1, András Szász1, Zsuzsanna Valkusz2

  • 1Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, 6703 Szeged, Hungary.

International journal of molecular sciences
|July 12, 2025
PubMed
概括

丁丁氨酸减小酶4 (PAD4) 通过中性粒细胞外细胞陷 (NET) 形成驱动1型糖尿病 (T1DM) 病原体. 用Cl-amidine抑制PAD4可降低NETosis,为T1DM提供一种潜在的治疗策略.

关键词:
在PAD4中使用PAD4.这就是STZ STZ.维斯塔尔老鼠是什么意思

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