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Updated: Sep 16, 2025

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通过综合虚拟查和分子动力学,基于结构的发现正性非性GLP-1R激活剂

Mansour S Alturki1, Reem A Alkhodier2,3, Mohamed S Gomaa1

  • 1Department of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.

International journal of molecular sciences
|July 12, 2025
PubMed
概括

针对2型糖尿病和肥胖症的新型非皮相对的葡萄糖类-1受体激动剂 (GLP-1RA) 已被确定. 自然产品库的计算选揭示了具有良好的药物动力学特征的有希望的候选药物.

关键词:
这是一个GLP-1RR.化学脚手架 化学脚手架分子动力学分子动力学口服治疗是一种口服疗法.虚拟选是虚拟的选.

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