微波辐射预处理作为一种可持续的方法,从羽中获得生物活性化物
Álvaro Torices-Hernández1, Marta Gallego1, Leticia Mora1
1Instituto de Agroquimica y Tecnologia de Alimentos (IATA-CSIC), Avenue Agustin Escardino 7, 46980 Paterna, Spain.
International journal of molecular sciences
|July 12, 2025
概括
微波辐射预处理增强了羽的水解,产生具有抗氧化,抗糖尿病和抗高血压特性的生物活性. 这种可持续的方法将家禽副产品重新利用,以获得潜在的健康益处.
科学领域:
- 生物技术是生物技术.
- 生物化学 生化学
- 材料科学 材料科学 材料科学
背景情况:
- 羽是家禽业的重要副产品,这给环境管理带来了挑战.
- 对羽毛废物的利用对于可持续的工业实践至关重要.
研究的目的:
- 开发一种可持续的方法,使用微波 (MW) 辐射和酶处理来化羽.
- 为了评估生物活性的生成从羽毛水解.
主要方法:
- 羽被用酸盐水解,有或没有先前的微波 (MW) 辐射预处理.
- 通过测量抗氧化剂, neprilysin 抑制剂, dipeptidyl peptidase IV (DPP IV) 和血管素转化酶 (ACE-I) 抑制活性来评估水解酸的生物活性.
- 用质谱和in silico分析来表征序列.
主要成果:
- 微波辐射预处理与酸盐水解 (MWA) 结合,产生了最高的抗氧化剂和 neprilysin 抑制活性 (55%).
- 没有MW预处理的化物显示出最高的DPP IV (约. 50%) 和ACE-I (大约. 70%) 的抑制性活动.
- 兆瓦的预处理提高了酸的水解效率,产生了多功能生物活性.
结论:
- 结合MW辐射和酶性水解,为羽的再利用提供了一个可持续的战略.
- 生产的生物活性具有潜在的抗氧化剂,抗糖尿病和抗高血压特性.
- 这种方法有助于减少浪费,并从家禽副产品中创造增值产品.
相关概念视频
00:46Bioremediation
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
01:26Physical Methods for Controlling Microbial Growth: Radiation and Filtration
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
01:25Microbial Bioremediation of Uranium
Microorganisms play a critical role in the transformation and immobilization of uranium in contaminated environments through four main pathways: bioreduction, biosorption, bioaccumulation, and biomineralization. These mechanisms reduce uranium’s toxicity and prevent its migration through groundwater systems, offering sustainable approaches for in situ bioremediation.Bioreduction of UraniumBioreduction is driven by anaerobic bacteria such as certain strains of Geobacter and Shewanella, which use...
01:30Microbial Wastewater Treatment
Microbial communities in aquatic ecosystems play a key role in the natural breakdown of contaminants introduced through domestic and industrial effluents. Acting as biological catalysts, these microbes change and mineralize a wide range of organic and inorganic pollutants under different redox conditions.In oxygen-rich surface waters, aerobic heterotrophs lead organic matter breakdown, using oxygen as the terminal electron acceptor to efficiently oxidize substrates to carbon dioxide and water.
01:27Upstream Processing
Upstream processing represents a critical phase in biomanufacturing, wherein biological systems such as microorganisms, mammalian cells, or insect cells are cultivated to produce therapeutic proteins, vaccines, enzymes, or other biologically derived products. This phase encompasses all steps from the selection and genetic manipulation of the production organism to the cultivation of cells in bioreactors under tightly controlled environmental conditions.Host Selection and Genetic OptimizationThe...
01:30Biological Treatment of Effluent and Waste Water
Biological wastewater treatment relies on the metabolic activity of microorganisms to remove pollutants from sewage. In modern treatment systems, this process is organized into sequential stages that progressively reduce solid material, dissolved organic matter, and microbial contamination. Each stage plays a distinct role in improving water quality and preparing the effluent for safe discharge or reuse.Primary and Secondary TreatmentPrimary treatment is a physical process that removes large...