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Updated: Sep 16, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

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建立临床GWAS的最佳实践:解决计算和数据质量挑战

Giorgio Casaburi1, Ron McCullough2, Valeria D'Argenio3,4

  • 1Department of Bioinformatics and Innovation Strategy, SOLVD Health, 1600 Faraday Ave., Carlsbad, CA 92008, USA.

International journal of molecular sciences
|July 12, 2025
PubMed
概括

在全基因组关联研究 (GWAS) 中的基因型归算可以提高变体覆盖率,但可以引入偏见,特别是对于罕见的变体和代表性不足的群体,影响精准医学的准确性和公平性.

关键词:
全基因组关联研究 (GWASs)基因类型的归算 基因类型的归算分子诊断 分子诊断 分子诊断精准医学是一门精准医学.

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