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在克罗恩氏病患者的内镜复发 患有长期乳房静脉修复的患者
Lotte Oldenburg1, Brecht Hens1,2, Maxime Hollenberg1
1Department of Gastroenterology and Hepatology, Amsterdam UMC, Location VUmc, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands.
Inflammatory bowel diseases
|July 12, 2025
概括
内镜性阴茎复发影响了近40%的克罗恩氏病.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠道疾病研究研究
- 外科手术的结果
背景情况:
- 克罗恩氏病 (CD) 管理通常涉及永久性结节切开.
- 与临床/手术复发相比,内镜复发在结节切开术中的研究不足.
研究的目的:
- 为了确定长期结节切开术患者内镜结节复发率.
- 为了识别与内镜内皮细胞复发相关的风险因素.
主要方法:
- 成年CD患者的回顾性研究 (≥12个月).
- 分析电子健康记录和内镜检查数据.
- 评估便calprotectin作为一个非侵入性标记.
主要成果:
- 116/150名患者接受了叶内镜检查;39.7%的患者出现了复发.
- 1,3年和5年的内镜复发率分别为11.2%,27.3%和33.0%.
- 较早的叶干扰和先前的生物治疗增加了复发风险 (HR 1.99, 2.48).
- 便calprotectin准确预测了内镜炎症 (89.9%的准确率).
结论:
- 近40%的长期结节切开术患者表现出内镜性结节复发.
- 患有先前阴茎干扰或生物暴露的患者需要更密切的内镜监测.
- 便中的calprotectin作为一个可靠的,非侵入性指标,以叶叶炎症.
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