在静止性性结肠炎患者中,使用高分辨率直肠测量检查的便性疾病患病率的研究
Khaled Abdel Aty1, Ezzat Ali Ali1, Eman Hamed Abu El-Soud1
1Internal Medicine department, Gastroenterology Unit, Faculty of Medicine, Alexandria University, Egypt.
概括
患有静止性性结肠炎 (UC) 的患者经常出现排便障碍. 建议使用高分辨率的直肠计量来评估UC患者的这些持续症状.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 生理学 生理学 生理学
背景情况:
- 性结肠炎 (UC) 涉及复发的结肠粘膜炎症.
- 排便障碍很常见,但在静止性UC中没有得到充分研究.
- 持续的症状会影响UC患者的生活质量.
研究的目的:
- 确定静止UC患者便障碍的患病率.
- 在这个人群中评估高分辨率直肠测量仪的实用性.
主要方法:
- 研究了一组50名UC患者在至少6个月内缓解或轻度活动的队列.
- 参与者有持续的排便症状 (便秘,失禁,紧迫性,疼痛,不完全的疏散).
- 方法包括病史,检查,实验室,结肠镜和高分辨率的直肠计量.
主要成果:
- 便失禁与疾病持续时间有统计学显著的关联 (P=0.008).
- 在排便障碍和UC延长或治疗之间没有发现显著的关联.
- 便秘,急迫性,不完全疏散和直肠痛缺乏与疾病持续时间,延长或治疗的统计学意义.
结论:
- 在性结肠炎患者中,即使在静止阶段,便障碍仍然存在.
- 高分辨率直肠计量是评估这些症状的宝贵工具.
- 早期检测和管理排便功能障碍对于UC患者的护理至关重要.
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