对水生生物微塑料诱导的生殖毒性的机制性见解:综合性综述
A K M Munzurul Hasan1, Md Foysul Hossain2, Minhaz Uddin3
1Department of Biology, University of Saskatchewan, Saskatoon SK, S7N 5E2, Canada.
Aquatic toxicology (Amsterdam, Netherlands)
|July 12, 2025
概括
微塑料污染水生生态系统,对生物体产生生殖和内分泌毒性. 本综述详细介绍了MP如何破坏荷尔蒙平衡并导致多代生殖障碍,强调了缓解的必要性.
科学领域:
- 环境毒理学环境毒理学
- 生态毒理学 生态毒理学
- 水生生态学 水生生态学
背景情况:
- 微塑料 (MP) 是普遍存在的水生污染物.
- 国会议员对水生生物和生态系统构成重大威胁.
- 它们的物理和化学特性促进生物积累和毒性.
研究的目的:
- 审查微塑料诱导的生殖和内分泌毒性的机制.
- 探索生物积累动态和分子途径.
- 综合对MP影响的研究,跨食用水平.
主要方法:
- 文献综述综合了关于微塑料毒性的最新研究.
- 分析MP的物理和化学特性.
- 对生物积累和分子信号通路的研究.
主要成果:
- 国会议员破坏荷尔蒙平衡,氧化应激和亡.
- 影响包括下丘脑-垂体-淋巴结轴功能受损,生育能力降低,并改变了游戏生成.
- 国会议员作为内分泌干扰化学品的载体,加剧了毒性.
结论:
- 微塑料污染导致水生物种多代繁殖障碍.
- 关键的信号通路 (MAPK,PI3K-AKT,mTOR,NF-κB,PPAR,NLRP3) 都会受到影响.
- 迫切需要减缓战略,法规和研究来保护水生生物多样性.
相关概念视频
Microbial Bioremediation of Hydrocarbons
161
Bioremediation is an environmentally sustainable process that employs living organisms—primarily microorganisms—to degrade or neutralize pollutants from contaminated environments. In oil spills and hydrocarbon pollution, bioremediation involves the use of hydrocarbon-degrading bacteria to transform toxic compounds into less harmful substances. This approach leverages natural microbial metabolic processes and is considered both cost-effective and ecologically favorable compared to...
161
Microbial Bioremediation of Pesticides
96
Pesticides often feature structurally complex chemical architectures, incorporating halogen groups and multiple aromatic rings. These characteristics confer high chemical stability, rendering many pesticides resistant to natural degradation processes. This resistance poses significant environmental concerns, as persistent pesticide residues can accumulate in ecosystems and affect non-target organisms.Despite the inherent stability of many pesticides, certain microorganisms possess the metabolic...
96
Microbial Bioremediation of Plastics
142
Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...
142


