孕产妇的vaping和怀孕不良结果:一个系统的审查和元分析
Alexandre Vallée1, Maha Eid2, Anis Feki3
1Department of Epidemiology and Public Health, Foch Hospital, Suresnes, France.
概括
与非吸烟者相比,孕妇在怀孕期间的电子烟显著增加了早产,低出生体重和怀孕年龄较小的婴儿的风险. 这些发现凸显了使用电子烟的孕妇的关键健康问题.
科学领域:
- 生殖健康 生殖健康
- 围产儿医学 围产儿医学
- 公共卫生 公共卫生
背景情况:
- 在孕妇中,电子烟的普及率越来越高,这引起了人们对尼古丁暴露的担忧.
- 现有的研究表明,怀孕期间与母亲的vaping相关的潜在风险.
- 这一元分析专门研究了与怀孕期间的电子烟有关的不良分娩结果.
研究的目的:
- 评估母亲的vaping和不良分娩结果之间的关联.
- 为了比较孕妇电子烟者与非吸烟者,烟草吸烟者和双重使用者之间的早产,低出生体重和怀孕年龄较小的风险.
- 提供基于证据的见解,了解电子烟对怀孕的影响.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在PubMed,科学网络和科克兰图书馆 (1986-2024) 中进行全面的文献搜索.
- 包括研究报告的早产,低出生体重,或怀孕年龄小的孕妇在孕妇vapers;概率比率 (ORs) 的聚合分析与95%的置信区间 (CI).
主要成果:
- 对9项涉及423,680名孕妇的研究进行了分析.
- 与非吸烟者相比,母亲的电子烟与早产风险增加40% (OR=1.40),低出生体重风险增加49% (OR=1.49) 和妊娠年龄小的风险增加32% (OR=1.32) 相关联.
- 与非吸烟者相比,vaping用户的怀孕年龄小的风险降低了47% (OR=0.53),与双重用户相比,风险降低了67% (OR=0.33).
结论:
- 怀孕期间的电子烟与早产,低出生体重和对妊娠年龄来说小的风险显著增加有关.
- 这些发现强调了解决孕妇戒烟问题的重要性.
- 进一步的研究可能会探索不同用户群体和不同暴露水平的细微影响.
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