当UV1癌症疫苗遇到免疫检查点封锁时:免疫反应是积极的,但临床结果是负的

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Updated: Sep 15, 2025

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
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Published on: July 7, 2023

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Guo Zhao1, Shuhang Wang1, Ning Li1

  • 1Clinical Trial Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Med (New York, N.Y.)
|July 12, 2025
PubMed
概括

结合Pembrolizumab的UV1疫苗并没有改善头癌患者的治疗结果. 虽然疫苗激活了T细胞,但与单独使用 pembrolizumab 相比,它没有提高临床疗效.

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