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Updated: Sep 15, 2025

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孟德尔随机化的多学集成识别了与内动脉瘤有因果关系的循环代谢物

Tianjie Liu1, Kuangyang Yu1, Chuying Wang1

  • 1Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

World neurosurgery
|July 12, 2025
PubMed
概括

这项研究确定了26种与内动脉瘤 (IA) 风险相关的血液代谢物,揭示了参与IA发展和潜在治疗标的CXCL8,SPP1和MMP9等关键基因.

关键词:
血液中的代谢产物.内动脉瘤是一个内动脉瘤.门德尔的随机化转录组分析 转录组分析qPCR验证的验证方法

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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