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Updated: Sep 15, 2025

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组织中空间分辨的微RNA表达:技术,挑战和机会

Agustín Robles-Remacho1, Yimin Zou1, Marco Grillo1

  • 1Science for Life Laboratory (SciLifeLab), Department of Biochemistry and Biophysics, Stockholm University, Solna, Sweden.

Trends in genetics : TIG
|July 12, 2025
PubMed
概括

空间miRNomics,研究微RNA (miRNA) 在组织中的表达,正在出现. 本综述探讨了用于基因调节研究的空间miRNA分析的当前技术,挑战和生物医学潜力.

关键词:
基因调节 基因调节 基因调节这就是miRNAs.微RNAs 是一个微型RNA.没有编码的RNAs.空间 miRNomics 的一个例子.空间的奥米克.空间转录学 空间转录学组织生物学 组织生物学

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MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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