老年外科手术患者的肉类和术后妄想之间的关联:系统性审查和元分析
Yunying Feng1,2, Ruixiao Sun3,4, Yuelun Zhang5
1Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
BMC geriatrics
|July 12, 2025
概括
肉,肌肉质量和力量的损失,显著增加了老年手术患者的术后妄想和不良结果的风险. 这一系统性审查证实了sarcopenia作为这些不良事件的独立预测因素.
科学领域:
- 老年医学 老年医学
- 手术结果研究研究.
- 肌肉生理学 肌肉生理学
背景情况:
- 肉症是老年人常见的疾病,涉及肌肉质量和力量的逐渐丧失.
- 它与不良术后结果的风险增加有关.
- 手术后妄想是老年手术患者的一个重大问题.
研究的目的:
- 对老年手术患者的手术后痴呆症对萨尔科佩尼亚的影响进行调查.
- 检查萨尔科佩尼亚和各种外科手术后期结果之间的关联.
- 通过系统性审查和元分析,综合现有研究的证据.
主要方法:
- 在主要数据库 (MEDLINE,EMBASE,CINAHL,Cochrane CENTRAL) 进行系统的文献搜索.
- 包括对老年外科手术患者的肉类和术后并发症的研究.
- 使用预后研究质量 (QUIPS) 工具进行偏差风险评估.
- 主要 (术后妄想) 和次要结果 (并发症,康复,生存) 的元分析.
主要成果:
- 萨科佩尼亚与术后狂妄症的发病率增加显著相关 (多变量OR2.42).
- 麻症患者面临整体术后并发症,死亡率和延迟恢复的更高风险.
- 亚组分析显示,在接受头部和部或心脏和胸部手术的麻患者中,总生存率降低的风险增加.
结论:
- 麻症是老年手术患者手术后痴呆症的强大,独立的预测因子.
- 肉类的存在与外科手术后的预后普遍较差和不良结果有关.
- 识别和潜在地管理肉症可以改善老年人手术的结果.
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