在接受口腔状细胞癌超选择性静脉内化学放射治疗的患者的传染性并发症
Hideaki Kato1,2, Takashi Ohya3, Toshiyuki Koizumi3
1Infection Prevention and Control Department, Yokohama City University Hospital, Yokohama, Japan.
Oral diseases
|July 13, 2025
概括
在口腔癌的超选择性动脉内化学放射治疗 (IACRT) 期间经常发生传染性并发症,这会对患者的预后产生负面影响. 密切监测和预防感染对于改善IACRT患者的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 医疗治疗 医疗治疗
背景情况:
- 超选择性动脉内化学辐射疗法 (IACRT) 是口腔癌的重要器官保护治疗方法.
- 在IACRT后感染并发症的发病率和预后意义尚未明确.
研究的目的:
- 为了研究接受IACRT的患者感染并发症的特征.
- 确定这些感染对患者结果的预后影响.
主要方法:
- 在2008年至2016年期间,对245名接受IACRT治疗的患者进行了回顾性审查.
- 患者组之间的传染性并发症率和类型的比较.
- 多变量回归分析以确定风险因素和预后指标.
主要成果:
- 54%的患者出现了184种传染性并发症,包括导管部位感染,血流感染,发烧性中性质减退,肺炎和C. difficile感染.
- 中枢静脉导管安置和3/4级中性质减退是感染并发症的重要危险因素.
- 与没有感染的患者 (79.4%) 相比,感染患者的5年整体存活率较低 (66.2%).
结论:
- 在IACRT期间的传染性并发症显著扰乱了癌症治疗,并恶化了患者的预后.
- 加强监测和积极的感染控制策略对于改善接受IACRT的口腔癌患者的生存率至关重要.
关键词:
化学疗法或放射治疗与设备相关的感染.发烧性中性质减肥症 发烧性中性质减肥症传染性并发症 传染性并发症动脉内导管 (catheter) 是一个动脉内导管.口腔癌是口腔癌的一种疾病.状细胞癌的癌症.更多相关视频
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