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Updated: Jun 22, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
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减少突发释放和增强基于SAIB的植入物中的持续释放:聚醇修饰的作用

Xue Wang1, Zao Ji2, Di Wu3

  • 1Department of Orthodontics, School of Stomatology, China Medical University, Shenyang, 110002, China.

European journal of medicinal chemistry
|July 13, 2025
PubMed
概括

用酸对阿里皮普拉 (ARP) 的多基修饰显著减少了从酸乙酸异酸盐 (SAIB) 植入物中的突发释放. 这种以药物为中心的策略通过改善30天的药物保留和控制释放来增强长效注射系统.

关键词:
这是一种阿里皮普拉衍生物.爆发释放抑制抑制 爆发释放抑制长效药物输送是长效药物输送.药物动力学增强剂 药物动力学增强剂用多醇修饰的前药物.基于SAIB的现场植入物植入物.

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