在手术后的头部和部癌症患者中,缺食症的可能临床预测因素
Christiane Hey1, Almut Goeze1, Jenny Hötzel1
1Department of Phoniatrics and Pediatric Audiology, Marburg University Hospital, Philipps University, Marburg, Germany.
概括
湿声等临床参数不能可靠地预测手术后头癌患者的消化不良. 建议在这个人群中进行水吞测试,以准确评估食障碍.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 语音语言病理学 语言病理学
背景情况:
- 缺食症是头癌 (HNC) 治疗后的一个常见并发症.
- 现有的临床参数用于食障碍评估通常在不同的患者群体 (中风,老年人群) 中得到验证.
- 这项研究评估了7个临床参数的预测质量,用于术后HNC患者的消化障碍.
研究的目的:
- 评估七个临床参数的质量标准,以预测HNC患者的缺食症.
- 为了确定单个和联合临床参数的预测能力,对食障碍,渴望和口服摄入限制.
- 确定可靠的临床工具,用于对HNC幸存者进行食障碍评估.
主要方法:
- 评估了184名手术后的HNC患者.
- 评估了七个核心临床参数及其组合.
- 菲相关性,交叉表格,逻辑回归和分类树被用来分析与透吸收量表和功能性口服摄入量表相比的预测准确性.
主要成果:
- 临床参数和失消症尺度之间的相关性很低,甚至不存在.
- 参数的灵敏度,特异性和效率对于缺食症预测是不令人满意的.
- 湿声在回归分析中显示出与消化不良,渴望和口服摄入限制的弱但显著的关联,但在分类树中没有.
结论:
- 目前的临床参数不足以预测HNC患者的缺食症.
- 没有任何单一的临床参数或组合被推用于常规临床使用.
- 建议在这个群体中进行水吞测试,以此作为更可靠的方法来评估食障碍.
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