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Updated: Sep 15, 2025

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
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在大动脉剖析中,HMGB2通过调节ROS-TLR4-NF-κB通路来调节光滑肌细胞的灭

Yao Mengge1, Xu Kunchen2, Li Jiakang3

  • 1The Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and pathophysiology, The School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.; Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, China.; Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fuzhou, China.; Hainan Women and Children's Medical Center, Haikou, China.

Cellular signalling
|July 13, 2025
PubMed
概括

高流动性组盒子2 (HMGB2) 通过促进炎症细胞死亡 (热死) 来驱动大动脉解剖 (AD). 针对HMGB2可能通过减少氧化应激和炎症来为AD提供新的治疗策略.

关键词:
动脉剖析是一个大动脉剖析.在HMGB2中,它是HMGB2.热灭菌的发生.这就是ROSOS ROS.在 TLR4/NF-κBB 中.

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