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使用pEGASUS-HPC支架用于急性破裂的宽内动脉瘤的支架辅助卷轴:一个多中心的回顾性研究

Abdallah Aburub¹, Zakarya Ali², Ali Khanafer³

¹Department of Diagnostic and Interventional Neuroradiology, University Hospital Marburg, Philipps-University Marburg, Marburg, Germany.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

|July 14, 2025

概括

在多中心研究中,pEGASUS-HPC支架是安全有效的治疗破裂的大脑宽动脉瘤,实现高闭塞率和良好的患者康复.

科学领域:

神经外科神经外科
干预性神经放射学干预性神经放射学
血管神经学血管神经学

背景情况:

支架辅助卷轴 (SAC) 是破裂的宽内动脉瘤的常见治疗方法.
佩加索-HPC支架,其性聚合物涂层 (HPC),旨在降低血栓发生率和提高在下大脑下出血 (SAH) 病例的安全性.

研究的目的:

评估pEGASUS-HPC支架的安全性和有效性,用于在患有破裂宽内动脉瘤的患者中进行支架辅助卷曲.

主要方法:

一项多中心回顾性队列研究包括22名在2021年7月至2024年6月期间接受pEGASUS-HPC SAC治疗的患者.
评估的结果包括手术成功,动脉瘤封闭 (修改的雷蒙德-罗伊分类,MRRC),临床结果 (修改的兰金尺度,mRS),并发症和死亡率.

主要成果:

所有手术都是成功的,在86.4%的病例中立即完全封闭 (MRRC I),在3个月后达到100%.
中位数mRS从出院时的3显著改善到最终随访时的0,表明持续恢复.
发生过渡性静脉栓塞的一个病例,保守地管理. 没有需要重新治疗. 死亡 (13.6%) 与严重的SAH等级和特定动脉瘤位置有关.

结论:

佩加索-HPC支架在治疗破裂的宽动脉瘤方面表现出良好的安全性和高疗效.
表面修饰型支架在SAH急性环境中可能是有益的.
需要进一步的前性研究来确认长期的安全性和有效性.

关键词:

动脉瘤是一个动脉瘤.卷轴绕卷轴绕在线佩加索斯-HPC公司支架是一种支架.脑下关节下部出血

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