β4,

Tung Him Ng1, Aijun Liang1,2, Maximus Cf Yeung1

  • 1Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 510282, P. R. China.

PubMed
概括

工程小细胞外囊泡 (sEVs) 富含整合素β4显示为肺癌治疗的希望. 这些装载着多克索鲁的XP-ITGβ4-sEV有效地向肺转移,并提高了安全性.

相关概念视频

Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...