低强度冲击波疗法用于治疗勃起功能障碍
Onuralp Ergun1,2, Kwangmin Kim3, Myung Ha Kim4
1Department of Urology, University of Minnesota, Minneapolis, Minnesota, USA.
The Cochrane database of systematic reviews
|July 14, 2025
概括
低强度冲击波疗法 (LiSWT) 可能为勃起功能障碍提供小益处,但临床重要性尚不确定. 这种治疗显示出长期改善的潜力,副作用最小.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 再生医学是一种再生医学.
- 性健康 性的健康
背景情况:
- 勃起功能障碍 (ED) 影响全球众多男性.
- 低强度冲击波疗法 (LiSWT) 是一种新兴的ED治疗方法.
- 现有的系统性审查缺乏严格的方法,并专注于患者重要的结果.
研究的目的:
- 为了评估LiSWT对ED的疗效和安全性,与假冒治疗相比.
- 评估关键结果,包括勃起功能,治疗中止和不良事件.
- 分析患者的重要结果,如满意度和生活质量.
主要方法:
- 一个全面的系统审查和随机对照试验 (RCT) 的元分析.
- 通过主要数据库 (科克兰图书馆,MEDLINE,Embase,Scopus) 和试验注册表进行的搜索.
- 包括21个RCT与1357名参与者,评估短期和长期的结果.
主要成果:
- LiSWT显示了勃起功能 (IIEF-EF评分) 的短期改善,小,可能不是临床重要.
- 长期勃起功能可能会改善,但证据的确定性很低.
- 与假药相比,治疗中止或不良事件没有显著差异.
- 阴茎刚性可能会在短期和长期改善,但临床意义值得怀疑.
结论:
- 在男性勃起功能障碍患者中,LiSWT可能对勃起功能提供适度的益处.
- 观察到的改善的临床重要性仍然不确定.
- 由于研究的局限性和潜在的偏见,证据的低确定性需要谨慎的解释.
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