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皮肤多聚质炎死亡率的趋势,1999-2022年:全国人口研究,美国

Elizabeth Matz¹, Ram R Singh¹

¹University of California at Los Angeles, Los Angeles, CA, 90095.

Arthritis care & research

|July 14, 2025

概括

皮肤多聚质炎 (DPM) 的死亡率比所有原因的死亡率下降得更快,直到COVID-19大流行. 然后,DPM死亡率与全因死亡率成比例增加,女性,年轻人以及某些种族/族群的相对死亡率更高.

科学领域:

流行病学流行病学
公共卫生公共卫生
类风湿病学类风湿病学

背景情况:

皮肤多聚质炎 (DPM) 是一种罕见的自身免疫性疾病,影响肌肉和皮肤.
了解DPM死亡率趋势对于公共卫生计划和患者护理至关重要.

研究的目的:

评估1999年至2022年美国皮肤多聚质炎 (DPM) 死亡率相对于所有原因死亡率的趋势.
确定具有差异性DPM死亡风险的人口亚组.

主要方法:

利用CDC数据库进行DPM和非DPM原因的全国死亡人数 (1999-2022年).
计算年龄标准化死亡率 (ASMR) 和它们的比率.
雇佣加入点回归分析年百分比变化 (APC) 在各种人口群体的死亡率和比率.

主要成果:

在疫情爆发之前,DPM死亡率每年下降幅度比非DPM死亡率 (-1.2%) 高 (-3.8%).
随着COVID-19大流行,DPM和全因死亡率均相应增加.
相对DPM死亡率在女性,年轻人 (≤64岁) 和非西班牙裔黑人,西班牙裔和非西班牙裔其他人口中高于白人.

结论:

DPM死亡率趋势反映了全因死亡率,流行病前的下降速度更快,流行病期间的比例上升.
在相对的DPM死亡率存在显著差异,跨性别,年龄和种族/种族.
强调需要加强查,早期干预和有针对性的战略,以解决DPM结果差异.

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