胸痛患病率和病假负担 1 个年后心肌梗塞与非阻塞性冠状动脉
Kerstin Welén Schef1, Per Tornvall2, Bertil Lindahl3
1Department of Clinical Sciences Danderyd Hospital, Karolinska Institutet Stockholm Sweden.
Journal of the American Heart Association
|July 14, 2025
概括
患有非阻塞性冠状动脉心肌梗塞 (MINOCA) 的患者比患有阻塞性冠状动脉疾病 (MI-CAD) 的患者更容易患上心痛和病假. 事件发生一年后,MINOCA患者报告生活质量恶化,表明严重的痛苦.
科学领域:
- 心脏病学 心脏病学
- 心血管研究研究心血管研究
- 内部医学 内部医学
背景情况:
- 心肌梗塞与非阻塞性冠状动脉 (MINOCA) 症状负担和疾病影响未得到充分研究.
- 米诺卡对患者的福祉产生影响,需要与阻塞性冠状动脉疾病 (MI-CAD) 进行比较分析.
研究的目的:
- 评估MINOCA患者的胸痛,1年患病率,病假和生活质量.
- 为了比较MINOCA和完全再血管化的MI-CAD患者之间的这些结果.
主要方法:
- 从SWEDEHEART注册表 (2005-2022) 分析了46428名第一次心肌梗塞的患者.
- 排除以前进行过干预,心力衰竭,心律失常或不完全再血管化的患者.
- 在1年的随访期望收集结果,比较MINOCA (n=5281) 和MI-CAD (n=41,157) 队列.
主要成果:
- 与MI-CAD相比,MINOCA患者的胸痛患病率较高 (11.6%与8.8%相比),病假增加1年 (13.4%与10.9%相比).
- 在MINOCA集团中,生活质量指标明显较低.
- 经过对混因素进行调整后,关联仍然很重要,尽管一些关联被减弱了.
结论:
- 米诺卡与患者的严重痛苦有关,包括心痛和病假的更高率.
- 与MI-CAD患者相比,MINOCA患者在指数事件发生一年后的生活质量更差.
- 这些发现强调了MINOCA对患者福祉的长期影响.
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