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Updated: Sep 15, 2025

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使用原子学模拟,阐明底层全长FUS形状转换的分子相互作用网络及其相位分离

Shuo-Lin Weng, Priyesh Mohanty, Jeetain Mittal

    bioRxiv : the preprint server for biology
    |July 14, 2025
    PubMed
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    全原子模拟揭示了液-液相分离 (LLPS) 过程中,Fused in Sarcoma (FUS) 蛋白域和内在无序区域如何相互作用. 这为FUS相关疾病和潜在的治疗点提供了分子洞察力.

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