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Updated: Jun 20, 2026

In Vitro Generation of Heart Field-specific Cardiac Progenitor Cells
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来自原始细胞的心脏球形用于研究心脏发育.

Cindy Chang, Juan Xu, Shirley Chang

    bioRxiv : the preprint server for biology
    |July 14, 2025
    PubMed
    概括

    研究人员使用初级小鼠细胞开发了新的心脏球形体,保留了疾病建模的体内特征. 这种主要细胞衍生方法为转化研究提供了干细胞方法的有希望的替代方案.

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    相关概念视频

    Development of the Heart01:27

    Development of the Heart

    The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
    As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...