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Updated: Sep 15, 2025

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein GST-RhoAG17A from Epithelial Cell Lysates
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Published on: March 31, 2012

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氨酸核酸交换因子EPAC1中的SUMO相互作用动机对于亚细胞向和功能是必需的

Wenli Yang1,2, Fang Mei1,2, Wei Lin1,2

  • 1Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, USA.

bioRxiv : the preprint server for biology
|July 14, 2025
PubMed
概括

EPAC1中的SUMO相互作用基因 (SIM) 对其与核孔综合体的相互作用和cAMP信号的调节至关重要. 破坏SIM会损害EPAC1的功能.

关键词:
这是RanBP2/Nup3588.这就是SUMOylation的作用.在CAMP中,我们可以使用cAMP.核包裹是一个核包裹.核孔复合体是核孔复合体.

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