获得的CRISPR间隔器和拉姆诺斯-葡萄糖多糖体缺陷使人对Streptococcus mutans菌APCM01产生抵抗力

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Updated: Sep 15, 2025

Generation of a Gene-disrupted Streptococcus mutans Strain Without Gene Cloning
12:06

Generation of a Gene-disrupted Streptococcus mutans Strain Without Gene Cloning

Published on: October 23, 2017

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Lucas A Wall1, Daniel Wall1

  • 1Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA.

bioRxiv : the preprint server for biology
|July 14, 2025
PubMed
概括

Streptococcus mutans 中的菌体耐药性可以通过CRISPR间隔器或rhamnose-glucose多糖基因突变而发展. 这些突变,虽然赋予了耐药性,但显著降低了细菌的适应性和生物膜的形成,限制了化潜力.

关键词:
这就是CRISR-Cas.突变型链球菌 (Streptococcus mutans) 是一种流感菌.细菌菌体是一种菌体.牙腐烂是指牙的腐烂.电阻的电阻是指电阻的电阻拉姆诺斯-葡萄糖多糖化物.

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