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Updated: Sep 15, 2025

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry
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Published on: November 23, 2011

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肝细胞MLKL在促进老化肝脏中线粒体功能障碍和衰老中的非正规作用

Sabira Mohammed, Chao Jiang, Travis Pennington

    bioRxiv : the preprint server for biology
    |July 14, 2025
    PubMed
    概括

    肝细胞中的MLKL过度表达驱动衰老和代谢功能障碍,而不是细胞死亡. 这一发现揭示了MLKL是肝脏衰老和炎症的关键因素,表明它是与年龄相关的肝脏疾病的治疗点.

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