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Updated: Sep 15, 2025

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通过辅因子亚斯酸盐对RNA脱甲基酶活性和选择性的差异控制

Lucas O Calzini1, Marcin Warminski2, Joanna Kowalska2

  • 1Department of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.

bioRxiv : the preprint server for biology
|July 14, 2025
PubMed
概括

对于Fe (II) -和2-氧格酸盐 (2-OG) -依赖的二氧化酶 (FOGDD) 酶,如FTO和AlkBH5.5,对酸盐 (维生素C) 的要求有很大差异. 这种维生素C辅因子选择性调节RNA脱甲基化,影响细胞调节.

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