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相关概念视频

Structures of the Endocrine System00:59

Structures of the Endocrine System

8.5K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
8.5K
An Overview of the Endocrine System01:10

An Overview of the Endocrine System

9.7K
The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
9.7K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

1.1K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
1.1K
Target Cell Response to Hormones01:22

Target Cell Response to Hormones

3.6K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
3.6K
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

1.6K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.6K
The Endocrine System01:29

The Endocrine System

708
The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
708

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Efficacy and Adherence to a Supervised Aerobic Exercise Training Intervention in Night-Shift Hospital Nurses: A Randomized Controlled Trial.

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Short-Term Combined Tat-Beclin1 and Endurance Training Improves Age-Related Decline in Physical Function in Male Mice.

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相关实验视频

Updated: Sep 15, 2025

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

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运动训练重塑器官间内分泌网络.

Cheehoon Ahn, Andrea L Hevener, Laurie J Goodyear

    bioRxiv : the preprint server for biology
    |July 14, 2025
    PubMed
    概括

    耐力运动重塑了器官通过分泌因素沟通的方式,揭示了新的"exerkines". 这项研究绘制了这些运动诱导的内分泌变化,强调脂肪组织和Wnt信号作为关键参与者.

    科学领域:

    • 生理学 生理学 生理学
    • 内分泌学 在内分泌学.
    • 系统生物学 系统生物学

    背景情况:

    • 运动触发了由分泌因素介导的全身分子变化.
    • 从体育训练中精确的内分泌网络变化还没有完全理解.

    研究的目的:

    • 通过耐力运动重塑的器官间内分泌通信全面绘制地图.
    • 确定新的运动诱导的分泌因子 (exerkines) 和它们的调节作用.

    主要方法:

    • 利用系统遗传学方法与耐力训练老鼠的多组织转录组学和蛋白质组学数据.
    • 分析了来自身体活动分子传感器联盟 (MoTrPaC) 的数据.

    主要成果:

    • 八周的耐力训练显著改变了多个器官对之间的内分泌效应.
    • 皮下白色脂肪组织被确定为一个关键的内分泌调节器.
    • 细胞外矩阵衍生因子和分泌Wnt信号因子是运动适应的关键媒介.

    结论:

    • 耐力练习彻底重塑了器官间的通信网络.
    • 这项研究为发现参与运动适应的新型运动基因提供了宝贵的资源.

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